Trade Names: | |
Synonyms: | |
Status: | Approved (1950) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | SI4064O0LX |
Parent Compound: | PROCAINAMIDE |
InChI Key | ABTXGJFUQRCPNH-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C13H22ClN3O |
Molecular Weight | 271.79 |
AlogP | 1.34 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 58.36 |
Molecular species | BASE |
Aromatic Rings | 1.0 |
Heavy Atoms | 17.0 |
Action | Mechanism of Action | Reference |
---|---|---|
BLOCKER | Sodium channel alpha subunit blocker | ISBN |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 104 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Atrial Fibrillation | 3 | D001281 | ClinicalTrials |
Heart Failure | 3 | D006333 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 8429 |
ChEMBL | CHEMBL605 |
EPA CompTox | DTXSID2049422 |
FDA SRS | SI4064O0LX |
Guide to Pharmacology | 4811 |
KEGG | C07401 |
PubChem | 66068 |
SureChEMBL | SCHEMBL40758 |
ZINC | ZINC01530756 |