Trade Names: | |
Synonyms: | |
Status: | Approved (1991) |
Entry Type: | Small molecule |
Molecule Category: | Salt Prodrug |
UNII: | 33067B3N2M |
Parent Compound: | QUINAPRIL |
InChI Key | IBBLRJGOOANPTQ-JKVLGAQCSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C25H31ClN2O5 |
Molecular Weight | 474.99 |
AlogP | 2.57 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 9.0 |
Polar Surface Area | 95.94 |
Molecular species | ACID |
Aromatic Rings | 2.0 |
Heavy Atoms | 32.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Angiotensin-converting enzyme inhibitor | DailyMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 110 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Hypertension | 4 | D006973 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 8714 |
ChEMBL | CHEMBL1201011 |
EPA CompTox | DTXSID3021221 |
FDA SRS | 33067B3N2M |
KEGG | C07340 |
PubChem | 54891 |
SureChEMBL | SCHEMBL41404 |