QUINIDINE GLUCONATE

Search structure
Trade Names:
Synonyms:
Status: Approved (1950)
Entry Type: Small molecule
Molecule Category: Salt
UNII: R6875N380F
Parent Compound: QUINIDINE

Structure
InChI Key XHKUDCCTVQUHJQ-LCYSNFERSA-N
Smile C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c1ccnc2ccc(OC)cc12.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
InChI=1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C26H36N2O9
Molecular Weight 520.58
AlogP 3.17
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 4.0
Polar Surface Area 45.59
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 24.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Sodium channel alpha subunit blocker DailyMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 103

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Blood and lymphatic system disorders
34.62
Renal and urinary disorders
15.38
Vascular disorders
11.54
Infections and infestations
7.69
Nervous system disorders
7.69
Psychiatric disorders
7.69
Cardiac disorders
3.85
General disorders and administration site conditions
3.85
Immune system disorders
3.85
Injury, poisoning and procedural complications
3.85

Cross References

Resources Reference
ChEBI 27502
ChEMBL CHEMBL1200437
FDA SRS R6875N380F
PubChem 94328
SureChEMBL SCHEMBL41479
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