Pharmacology

Action Mechanism of Action Reference
INHIBITOR Vascular endothelial growth factor A inhibitor DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Macular Edema 4 D008269 ClinicalTrials
Diabetic Retinopathy 4 D003930 ClinicalTrials
Macular Degeneration 3 D008268 ClinicalTrials
Glaucoma 3 D005901 ClinicalTrials
Retinal Vein Occlusion 3 D012170 ClinicalTrials
Macular Degeneration 3 D008268 ClinicalTrials
Retinopathy of Prematurity 3 D012178 ClinicalTrials
Myopia, Degenerative 3 D047728 ClinicalTrials
Blindness 3 D001766 ClinicalTrials
Glaucoma, Neovascular 3 D015355 ClinicalTrials
Histoplasmosis 2 D006660 ClinicalTrials
Pterygium 2 D011625 ClinicalTrials
Telangiectasis 2 D013684 ClinicalTrials
Retinoblastoma 2 D012175 ClinicalTrials
Retinal Diseases 2 D012164 ClinicalTrials
Retinal Detachment 2 D012163 ClinicalTrials
Diabetes Mellitus 2 D003920 ClinicalTrials
Port-Wine Stain 1 D019339 ClinicalTrials
Myopia 1 D009216 ClinicalTrials
Corneal Neovascularization 1 D016510 ClinicalTrials
Optic Neuropathy, Ischemic 1 D018917 ClinicalTrials
Glaucoma, Open-Angle 1 D005902 ClinicalTrials
Angioid Streaks 1 D000793 ClinicalTrials
von Hippel-Lindau Disease 1 D006623 ClinicalTrials
Central Serous Chorioretinopathy 1 D056833 ClinicalTrials
Conjunctival Neoplasms 1 D003230 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Eye disorders
31.12
Nervous system disorders
13.63
Vascular disorders
12.32
General disorders and administration site conditions
8.32
Injury, poisoning and procedural complications
7.09
Cardiac disorders
3.7
Infections and infestations
2.99
Respiratory, thoracic and mediastinal disorders
2.68
Musculoskeletal and connective tissue disorders
2.67
Investigations
2.39

Cross References

Resources Reference
CAS NUMBER 347396-82-1
ChEMBL CHEMBL1201825
FDA SRS ZL1R02VT79
Guide to Pharmacology 6779