RIZATRIPTAN BENZOATE

Search structure
Trade Names:
Synonyms:
Status: Approved (1998)
Entry Type: Small molecule
Molecule Category: Salt
UNII: WR978S7QHH
Parent Compound: RIZATRIPTAN

Structure
InChI Key JPRXYLQNJJVCMZ-UHFFFAOYSA-N
Smile CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12.O=C(O)c1ccccc1
InChI
InChI=1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H25N5O2
Molecular Weight 391.48
AlogP 1.91
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 49.74
Molecular species BASE
Aromatic Rings 3.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Serotonin 1b (5-HT1b) receptor agonist FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Migraine with Aura 3 D020325 ClinicalTrials
Migraine without Aura 3 D020326 ClinicalTrials

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
17.79
Nervous system disorders
15.67
Gastrointestinal disorders
9.09
Vascular disorders
8.34
Injury, poisoning and procedural complications
6.68
Psychiatric disorders
6.42
Cardiac disorders
4.53
Skin and subcutaneous tissue disorders
3.98
Investigations
3.81
Musculoskeletal and connective tissue disorders
3.71
Respiratory, thoracic and mediastinal disorders
3.26
Product issues
3.16
Immune system disorders
2.83
Pregnancy, puerperium and perinatal conditions
2.22

Cross References

Resources Reference
ChEBI 8875
ChEMBL CHEMBL1201032
EPA CompTox DTXSID20162937
FDA SRS WR978S7QHH
Guide to Pharmacology 51
KEGG D08485
PubChem 77997
SureChEMBL SCHEMBL41226
ZINC ZINC00005895
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