SIBUTRAMINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1997) Withdrawn (2010)
Entry Type: Small molecule
Molecule Category: Salt
UNII: OGM0YHD1WF
Parent Compound: SIBUTRAMINE

Structure
InChI Key UWAOJIWUVCMBAZ-UHFFFAOYSA-N
Smile CC(C)CC(N(C)C)C1(c2ccc(Cl)cc2)CCC1.Cl
InChI
InChI=1S/C17H26ClN.ClH/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;/h6-9,13,16H,5,10-12H2,1-4H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H29Cl2NO
Molecular Weight 334.33
AlogP 4.74
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 5.0
Polar Surface Area 3.24
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 19.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Monoamine transporter inhibitor FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Obesity 3 D009765 ClinicalTrials

Related Entries

Scaffolds

Parent

Cross References

Resources Reference
ChEMBL CHEMBL3989830
FDA SRS OGM0YHD1WF
Guide to Pharmacology 2586
KEGG C07247
PubChem 64765
SureChEMBL SCHEMBL42301
ZINC ZINC00531272
CONTENTS