| Trade Names: | |
| Synonyms: | |
| Status: | Approved (2018) |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | N03AX17 |
| UNII: | R02XOT8V8I |
Structure
| InChI Key | IBLNKMRFIPWSOY-FNORWQNLSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C14H18O3 |
| Molecular Weight | 234.29 |
| AlogP | 2.84 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 2.0 |
| Polar Surface Area | 38.69 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 17.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Ligand-gated ion channel
GABA-A receptor
|
46000 | - | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Epilepsies, Myoclonic | 4 | D004831 | FDA |
| Hyperoxaluria, Primary | 2 | D006960 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 49763-96-4 |
| ChEMBL | CHEMBL1983350 |
| DrugBank | DB09118 |
| EPA CompTox | DTXSID6049068 |
| FDA SRS | R02XOT8V8I |
| Guide to Pharmacology | 5469 |
| PubChem | 5311454 |
| SureChEMBL | SCHEMBL216436 |
CONTENTS