AFABICIN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: DMM8663H2R

Structure
InChI Key HFYMDQMXVPJNTH-VQHVLOKHSA-N
Smile Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CCC(=O)N3COP(=O)(O)O)oc2ccccc12
InChI
InChI=1S/C23H24N3O7P/c1-15-18-5-3-4-6-19(18)33-20(15)13-25(2)21(27)9-7-16-11-17-8-10-22(28)26(23(17)24-12-16)14-32-34(29,30)31/h3-7,9,11-12H,8,10,13-14H2,1-2H3,(H2,29,30,31)/b9-7+

Physicochemical Descriptors

Property Name Value
Molecular Formula C23H24N3O7P
Molecular Weight 485.43
AlogP 3.15
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 7.0
Polar Surface Area 133.41
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 34.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Enoyl-[acyl-carrier-protein] reductase [NADPH] inhibitor Other PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Infections 2 D007239 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 1518800-35-5
ChEMBL CHEMBL4297501
DrugBank DB15268
FDA SRS DMM8663H2R
Guide to Pharmacology 10754
PubChem 72696796
SureChEMBL SCHEMBL15479062
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