AMDOXOVIR

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 54I81H0M9C

Structure
InChI Key RLAHNGKRJJEIJL-RFZPGFLSSA-N
Smile Nc1nc(N)c2ncn([C@H]3CO[C@@H](CO)O3)c2n1
InChI
InChI=1S/C9H12N6O3/c10-7-6-8(14-9(11)13-7)15(3-12-6)4-2-17-5(1-16)18-4/h3-5,16H,1-2H2,(H4,10,11,13,14)/t4-,5-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H12N6O3
Molecular Weight 252.23
AlogP -1.15
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 2.0
Polar Surface Area 134.33
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 18.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Human immunodeficiency virus type 1 reverse transcriptase inhibitor PubMed PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
HIV Infections 2 D015658 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 145514-04-1
ChEMBL CHEMBL458876
DrugBank DB06619
FDA SRS 54I81H0M9C
PubChem 124088
SureChEMBL SCHEMBL141228
ZINC ZINC000003919810
CONTENTS