Synonyms: | |
Status: | Approved (1961) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
ATC: | N06AA09 |
UNII: | 1806D8D52K |
InChI Key | KRMDCWKBEZIMAB-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C20H23N |
Molecular Weight | 277.41 |
AlogP | 4.17 |
Hydrogen Bond Acceptor | 1.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 3.0 |
Polar Surface Area | 3.24 |
Molecular species | BASE |
Aromatic Rings | 2.0 |
Heavy Atoms | 21.0 |
Primary Target | |
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H1 receptor | |
M1 receptor | |
M2 receptor | |
M3 receptor | |
M4 receptor | |
M5 receptor | |
NET | |
SERT |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Depressive Disorder | 4 | D003866 | ClinicalTrials |
Migraine Disorders | 3 | D008881 | ClinicalTrials |
Pain | 3 | D010146 | ClinicalTrials |
Neuralgia | 3 | D009437 | ClinicalTrials |
Schizophrenia | 3 | D012559 | ClinicalTrials |
Sleep Initiation and Maintenance Disorders | 3 | D007319 | ClinicalTrials |
Anxiety | 3 | D001007 | ClinicalTrials |
Fibromyalgia | 3 | D005356 | ClinicalTrials |
Dementia | 3 | D003704 | ClinicalTrials |
Headache | 3 | D006261 | ClinicalTrials |
Cystitis, Interstitial | 3 | D018856 | ClinicalTrials |
Depressive Disorder, Major | 3 | D003865 | ClinicalTrials |
Peripheral Nervous System Diseases | 2 | D010523 | ClinicalTrials |
Intervertebral Disc Displacement | 2 | D007405 | ClinicalTrials |
Paget Disease, Extramammary | 2 | D010145 | ClinicalTrials |
Digestive System Diseases | 2 | D004066 | ClinicalTrials |
Diabetes Mellitus | 2 | D003920 | ClinicalTrials |
Biliary Dyskinesia | 2 | D001657 | ClinicalTrials |
Bursitis | 2 | D002062 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 50-48-6 |
ChEBI | 2666 |
ChEMBL | CHEMBL629 |
DrugBank | DB00321 |
DrugCentral | 180 |
EPA CompTox | DTXSID7022594 |
FDA SRS | 1806D8D52K |
Human Metabolome Database | HMDB0014466 |
Guide to Pharmacology | 200 |
KEGG | C06824 |
PDB | TP0 |
PharmGKB | PA448385 |
PubChem | 2160 |
SureChEMBL | SCHEMBL7824 |
ZINC | ZINC000000968257 |