| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | H464ZO600O |
Structure
| InChI Key | MXPOCMVWFLDDLZ-NSCUHMNNSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C15H16N2O4 |
| Molecular Weight | 288.3 |
| AlogP | 0.1 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 4.0 |
| Polar Surface Area | 82.54 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 21.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | DNA inhibitor | PubMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | - | - | - | 5 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Urinary Bladder Neoplasms | 3 | D001749 | ClinicalTrials |
| Urinary Bladder Neoplasms | 3 | D001749 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 114560-48-4 |
| ChEMBL | CHEMBL73822 |
| DrugBank | DB12593 |
| FDA SRS | H464ZO600O |
| PubChem | 5813717 |
| SureChEMBL | SCHEMBL367964 |
| ZINC | ZINC000001536777 |
CONTENTS