| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | LPU25F15UQ |
Structure
| InChI Key | KJNNWYBAOPXVJY-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C32H38ClN3O2 |
| Molecular Weight | 532.13 |
| AlogP | 8.44 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 14.0 |
| Polar Surface Area | 39.52 |
| Molecular species | BASE |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 38.0 |
Pharmacology
| Primary Target | |
|---|---|
| advanced glycosylation end-product specific receptor |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Unclassified protein
|
- | - | 500 | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Alzheimer Disease | 3 | D000544 | ClinicalTrials |
| Diabetic Nephropathies | 2 | D003928 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 603148-36-3 |
| ChEMBL | CHEMBL3989929 |
| DrugBank | DB12689 |
| FDA SRS | LPU25F15UQ |
| Guide to Pharmacology | 8317 |
| PubChem | 11180124 |
| SureChEMBL | SCHEMBL1142599 |
| ZINC | ZINC000038336973 |
CONTENTS