BELORANIB

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: FI471K8BU6

Structure
InChI Key ZEZFKUBILQRZCK-MJSCXXSSSA-N
Smile CO[C@H]1[C@H]([C@@]2(C)O[C@@H]2CC=C(C)C)[C@]2(CC[C@H]1OC(=O)/C=C/c1ccc(OCCN(C)C)cc1)CO2
InChI
InChI=1S/C29H41NO6/c1-20(2)7-13-24-28(3,36-24)27-26(32-6)23(15-16-29(27)19-34-29)35-25(31)14-10-21-8-11-22(12-9-21)33-18-17-30(4)5/h7-12,14,23-24,26-27H,13,15-19H2,1-6H3/b14-10+/t23-,24-,26-,27-,28+,29+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C29H41NO6
Molecular Weight 499.65
AlogP 4.26
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 11.0
Polar Surface Area 73.06
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 36.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Methionine aminopeptidase 2 inhibitor PubMed PubMed
Primary Target
Methionyl aminopeptidase 2

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Prader-Willi Syndrome 3 D011218 ClinicalTrials
Obesity 2 D009765 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 251111-30-5
ChEMBL CHEMBL4297504
DrugBank DB12671
EPA CompTox DTXSID40179800
FDA SRS FI471K8BU6
Guide to Pharmacology 8445
PubChem 6918502
SureChEMBL SCHEMBL14648763
ZINC ZINC000003982162
CONTENTS