BICIFADINE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: B0SV3N7J3H

Structure
InChI Key OFYVIGTWSQPCLF-UHFFFAOYSA-N
Smile Cc1ccc(C23CNCC2C3)cc1
InChI
InChI=1S/C12H15N/c1-9-2-4-10(5-3-9)12-6-11(12)7-13-8-12/h2-5,11,13H,6-8H2,1H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C12H15N
Molecular Weight 173.26
AlogP 1.86
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 12.03
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 13.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Monoamine transporter inhibitor PubMed Other
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel
- 44668 - - -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- 117 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Low Back Pain 3 D017116 ClinicalTrials
Diabetic Neuropathies 2 D003929 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 71195-57-8
ChEMBL CHEMBL511099
DrugBank DB04889
FDA SRS B0SV3N7J3H
PubChem 24768032
SureChEMBL SCHEMBL38793
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