Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | A3MMS6HDO1 |
InChI Key | VNBRGSXVFBYQNN-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C25H19ClF2N4O4 |
Molecular Weight | 512.9 |
AlogP | 5.19 |
Hydrogen Bond Acceptor | 7.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 7.0 |
Polar Surface Area | 108.47 |
Molecular species | NEUTRAL |
Aromatic Rings | 4.0 |
Heavy Atoms | 36.0 |
Primary Target | |
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macrophage stimulating 1 receptor | |
MET proto-oncogene, receptor tyrosine kinase |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Neoplasms | 1 | D009369 | ClinicalTrials |
Resources | Reference |
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CAS NUMBER | 1025720-94-8 |
ChEBI | 91409 |
ChEMBL | CHEMBL460702 |
DrugBank | DB12064 |
EPA CompTox | DTXSID50145278 |
FDA SRS | A3MMS6HDO1 |
Guide to Pharmacology | 7953 |
PDB | 353 |
PubChem | 24794418 |
SureChEMBL | SCHEMBL2588311 |
ZINC | ZINC000039716080 |