| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | U2Y5OFN795 |
Structure
| InChI Key | LTEJRLHKIYCEOX-OCCSQVGLSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C22H24FN5O4 |
| Molecular Weight | 441.46 |
| AlogP | 3.42 |
| Hydrogen Bond Acceptor | 8.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 116.76 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 32.0 |
Pharmacology
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Colorectal Neoplasms | 3 | D015179 | ClinicalTrials |
| Carcinoma, Renal Cell | 2 | D002292 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
| Carcinoma, Hepatocellular | 1 | D006528 | ClinicalTrials |
Related Entries
MCS
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 649735-63-7 |
| ChEBI | 167656 |
| ChEMBL | CHEMBL270995 |
| DrugBank | DB11865 |
| EPA CompTox | DTXSID20215295 |
| FDA SRS | U2Y5OFN795 |
| Guide to Pharmacology | 8097 |
| PubChem | 11154925 |
| SureChEMBL | SCHEMBL483382 |
| ZINC | ZINC000029134440 |
CONTENTS