Synonyms: | |
Status: | Phase 2 |
Entry Type: | Protein |
Molecule Category: | UNKNOWN |
UNII: | GZ8FA500J0 |
InChI Key | NSQLIUXCMFBZME-MPVJKSABSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C127H203N45O39S3 |
Molecular Weight | 3080.5 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Atrial natriuretic peptide receptor agonist | PubMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
Lyase
Guanylate cyclase
Receptor guanylate cyclase
|
0 | - | - | - | - | |
Membrane receptor
|
1 | - | - | - | - |
Mesh Heading | Maximum Phase | Reference |
---|---|---|
Cardiomyopathies; Heart Failure; Ventricular Dysfunction; Ventricular Dysfunction, Left | Phase 2 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 135914 |
ChEMBL | CHEMBL2104386 |
DrugCentral | 515 |
FDA SRS | GZ8FA500J0 |
SureChEMBL | SCHEMBL218549 |