CEFTAROLINE

Search structure
Synonyms:
Status: Approved
Entry Type: Unknown
Molecule Category: UNKNOWN

Structure
InChI Key RGFBRLNVZCCMSV-BIRGHMBHSA-N
Smile CCO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(Sc3nc(-c4cc[n+](C)cc4)cs3)CS[C@H]12)c1nsc(N)n1
InChI
InChI=1S/C22H20N8O5S4/c1-3-35-27-13(16-26-21(23)39-28-16)17(31)25-14-18(32)30-15(20(33)34)12(9-36-19(14)30)38-22-24-11(8-37-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H3-,23,25,26,28,31,33,34)/b27-13-/t14-,19-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H20N8O5S4
Molecular Weight 604.72
AlogP -0.04
Hydrogen Bond Acceptor 14.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 9.0
Polar Surface Area 179.7
Molecular species None
Aromatic Rings 3.0
Heavy Atoms 39.0

Indications

Mesh Heading Maximum Phase Reference
Bacterial Infections; Communicable Diseases; Infection Phase 3 ClinicalTrials
Cellulitis; Communicable Diseases; Infection; Skin Diseases; Skin Diseases, Infectious; Staphylococcal Skin Infections Phase 4 ClinicalTrials
Pneumonia; Pneumonia, Bacterial Phase 3 ClinicalTrials
Bacteremia Phase 4 ClinicalTrials
Pneumonia Phase 4 ClinicalTrials
Cystic Fibrosis; Fibrosis Phase 4 ClinicalTrials
Pneumonia Phase 1 ClinicalTrials
Arthritis, Infectious; Bacteremia; Endocarditis; Healthcare-Associated Pneumonia; Osteomyelitis; Pneumonia Phase 4 ClinicalTrials
Bacterial Infections; Communicable Diseases; Infection; Skin Diseases, Bacterial Phase 2 ClinicalTrials
Fractures, Bone; Fractures, Open Phase 4 ClinicalTrials
Bacterial Infections; Communicable Diseases; Infection Phase 3 ClinicalTrials
Pneumonia; Pneumonia, Bacterial Phase 4 ClinicalTrials
Infection; Surgical Wound Infection Phase 4 ClinicalTrials
Arthritis, Infectious; Communicable Diseases; Infection; Osteomyelitis Phase 4 ClinicalTrials

Related Entries

MCS

Scaffolds

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