Synonyms:
Status: Phase 2
Entry Type: Antibody
Molecule Category: UNKNOWN
UNII: 2285XW22DR

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Insulin-like growth factor I receptor antagonist PMC

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Colonic Neoplasms 2 D003110 ClinicalTrials
Carcinoma, Hepatocellular 2 D006528 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 2 D064129 ClinicalTrials
Lung Neoplasms 2 D008175 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Carcinoma, Squamous Cell 2 D002294 ClinicalTrials
Mesothelioma 2 D008654 ClinicalTrials
Melanoma 2 D008545 ClinicalTrials
Rhabdomyosarcoma, Alveolar 2 D018232 ClinicalTrials
Rhabdomyosarcoma, Embryonal 2 D018233 ClinicalTrials
Osteosarcoma 2 D012516 ClinicalTrials
Small Cell Lung Carcinoma 2 D055752 ClinicalTrials
Carcinoma, Large Cell 2 D018287 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 2 D002289 ClinicalTrials
Head and Neck Neoplasms 2 D006258 ClinicalTrials
Colorectal Neoplasms 2 D015179 ClinicalTrials
Adenocarcinoma of Lung 2 D000077192 ClinicalTrials
Adrenal Cortex Neoplasms 2 D000306 ClinicalTrials
Rectal Neoplasms 2 D012004 ClinicalTrials
Sarcoma 2 D012509 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials
Pancreatic Neoplasms 1 D010190 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials
Breast Neoplasms, Male 1 D018567 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 947687-12-9
ChEMBL CHEMBL1743001
FDA SRS 2285XW22DR