CONTEZOLID ACEFOSAMIL

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN Prodrug
UNII: CJZ0KB5903

Structure
InChI Key YCRAGJLWFBGKFE-CYBMUJFWSA-N
Smile CC(=O)OP(=O)(O)N(C[C@H]1CN(c2cc(F)c(N3C=CC(=O)CC3)c(F)c2F)C(=O)O1)c1ccon1
InChI
InChI=1S/C20H18F3N4O8P/c1-11(28)35-36(31,32)27(16-4-7-33-24-16)10-13-9-26(20(30)34-13)15-8-14(21)19(18(23)17(15)22)25-5-2-12(29)3-6-25/h2,4-5,7-8,13H,3,6,9-10H2,1H3,(H,31,32)/t13-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H17F3N4NaO8P
Molecular Weight 552.33
AlogP 2.88
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 7.0
Polar Surface Area 142.72
Molecular species ACID
Aromatic Rings 2.0
Heavy Atoms 36.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial 70S ribosome inhibitor PubMed

Indications

Mesh Heading Maximum Phase Reference
Bacterial Infections; Communicable Diseases; Gram-Positive Bacterial Infections; Infection; Skin Diseases; Skin Diseases, Bacterial Phase 2 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4301914
FDA SRS CJZ0KB5903
Guide to Pharmacology 10796
PubChem 131750213
SureChEMBL SCHEMBL17032472
ChEMBL CHEMBL3989966
FDA SRS T79C086548
PubChem 131750213
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