CPI-0610

Search structure
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 306QR91I9R

Structure
InChI Key GCWIQUVXWZWCLE-INIZCTEOSA-N
Smile Cc1noc2c1-c1ccccc1C(c1ccc(Cl)cc1)=N[C@H]2CC(N)=O
InChI
InChI=1S/C20H16ClN3O2/c1-11-18-14-4-2-3-5-15(14)19(12-6-8-13(21)9-7-12)23-16(10-17(22)25)20(18)26-24-11/h2-9,16H,10H2,1H3,(H2,22,25)/t16-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H16ClN3O2
Molecular Weight 365.82
AlogP 4.07
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 81.48
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 26.0

Indications

Mesh Heading Maximum Phase Reference
Multiple Myeloma; Neoplasms, Plasma Cell Phase 1 ClinicalTrials
Lymphoma Phase 1 ClinicalTrials
Leukemia, Myeloid; Leukemia, Myeloid, Acute; Myelodysplastic-Myeloproliferative Diseases; Myelodysplastic Syndromes; Myeloproliferative Disorders; Primary Myelofibrosis Phase 1/Phase 2 ClinicalTrials
Nerve Sheath Neoplasms; Neurofibrosarcoma; Peripheral Nervous System Neoplasms Phase 2 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL4303404
FDA SRS 306QR91I9R
Guide to Pharmacology 9120
PDB 62G
SureChEMBL SCHEMBL15926539
ZINC ZINC000200480149
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