ELTOPRAZINE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 510M006KO6

Structure
InChI Key WVLHGCRWEHCIOT-UHFFFAOYSA-N
Smile c1cc2c(c(N3CCNCC3)c1)OCCO2
InChI
InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2

Physicochemical Descriptors

Property Name Value
Molecular Formula C12H16N2O2
Molecular Weight 220.27
AlogP 0.87
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 33.73
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 16.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
- - 15849-16000 - -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Dopamine receptor
- - - 1100 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Serotonin receptor
- - - 9-40 -

Indications

Mesh Heading Maximum Phase Reference
Cognitive Dysfunction; Schizophrenia Phase 2 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 98224-03-4
ChEMBL CHEMBL282614
DrugBank DB12883
EPA CompTox DTXSID5048425
FDA SRS 510M006KO6
PubChem 65853
SureChEMBL SCHEMBL177715
ZINC ZINC000000001347
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