| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| UNII: | R6D2UI4FLS |
Structure
| InChI Key | GKIRPKYJQBWNGO-OCEACIFDSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C26H28ClNO |
| Molecular Weight | 405.97 |
| AlogP | 6.56 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 12.47 |
| Molecular species | BASE |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 29.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Isomerase
|
- | - | - | 1 | - | |
|
Membrane receptor
|
- | - | - | 8 | - | |
|
Unclassified protein
|
- | 3700 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Obesity | 2 | D009765 | ClinicalTrials |
| Hypogonadism | 2 | D007006 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 15690-57-0 |
| ChEMBL | CHEMBL954 |
| DrugBank | DB06735 |
| FDA SRS | R6D2UI4FLS |
| Guide to Pharmacology | 7619 |
| PDB | 53Q |
| PubChem | 1548953 |
| SureChEMBL | SCHEMBL34893 |
| ZINC | ZINC000001530601 |
CONTENTS