Synonyms: | |
Status: | Phase 3 |
Entry Type: | Small molecule |
Molecule Category: | Parent |
UNII: | UC96G28EQF |
InChI Key | AXRCEOKUDYDWLF-UHFFFAOYSA-N |
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Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C32H29N5O2 |
Molecular Weight | 515.62 |
AlogP | 4.93 |
Hydrogen Bond Acceptor | 6.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 5.0 |
Polar Surface Area | 72.16 |
Molecular species | NEUTRAL |
Aromatic Rings | 5.0 |
Heavy Atoms | 39.0 |
Primary Target | |
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protein kinase C beta |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Glioblastoma | 3 | D005909 | ClinicalTrials |
Lymphoma, Non-Hodgkin | 3 | D008228 | ClinicalTrials |
Neoplasms | 2 | D009369 | ClinicalTrials |
Lymphoma, Follicular | 2 | D008224 | ClinicalTrials |
Lymphoma, T-Cell, Cutaneous | 2 | D016410 | ClinicalTrials |
Glioma | 2 | D005910 | ClinicalTrials |
Colorectal Neoplasms | 2 | D015179 | ClinicalTrials |
Lymphoma, Large B-Cell, Diffuse | 2 | D016403 | ClinicalTrials |
Carcinoma, Renal Cell | 2 | D002292 | ClinicalTrials |
Small Cell Lung Carcinoma | 2 | D055752 | ClinicalTrials |
Multiple Myeloma | 2 | D009101 | ClinicalTrials |
Carcinoma, Non-Small-Cell Lung | 2 | D002289 | ClinicalTrials |
Pancreatic Neoplasms | 2 | D010190 | ClinicalTrials |
Glioma | 2 | D005910 | ClinicalTrials |
Lymphoma | 2 | D008223 | ClinicalTrials |
Lymphoma, Follicular | 2 | D008224 | ClinicalTrials |
Lymphoma, Mantle-Cell | 2 | D020522 | ClinicalTrials |
Colorectal Neoplasms | 2 | D015179 | ClinicalTrials |
Waldenstrom Macroglobulinemia | 2 | D008258 | ClinicalTrials |
Fallopian Tube Neoplasms | 2 | D005185 | ClinicalTrials |
Peritoneal Neoplasms | 2 | D010534 | ClinicalTrials |
Breast Neoplasms | 2 | D001943 | ClinicalTrials |
Ovarian Neoplasms | 2 | D010051 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
Lung Neoplasms | 2 | D008175 | ClinicalTrials |
Gliosarcoma | 1 | D018316 | ClinicalTrials |
Leukemia, Lymphoid | 1 | D007945 | ClinicalTrials |
Resources | Reference |
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CAS NUMBER | 170364-57-5 |
ChEBI | 91368 |
ChEMBL | CHEMBL300138 |
DrugBank | DB06486 |
EPA CompTox | DTXSID5044029 |
FDA SRS | UC96G28EQF |
Guide to Pharmacology | 5693 |
PubChem | 176167 |
SureChEMBL | SCHEMBL678748 |
ZINC | ZINC000001494900 |