Synonyms: | |
Status: | Approved (2010) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
ATC: | L01XX41 |
UNII: | LR24G6354G |
InChI Key | UFNVPOGXISZXJD-JBQZKEIOSA-N |
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Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C40H59NO11 |
Molecular Weight | 729.91 |
AlogP | 3.44 |
Hydrogen Bond Acceptor | 12.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 4.0 |
Polar Surface Area | 146.39 |
Molecular species | BASE |
Aromatic Rings | 0.0 |
Heavy Atoms | 52.0 |
Primary Target | |
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tubulin beta class I |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Neoplasms | 4 | D009369 | ClinicalTrials |
Carcinoma, Non-Small-Cell Lung | 3 | D002289 | ClinicalTrials |
Breast Neoplasms | 3 | D001943 | ClinicalTrials |
Breast Neoplasms | 3 | D001943 | ClinicalTrials |
Inflammatory Breast Neoplasms | 2 | D058922 | ClinicalTrials |
Hereditary Breast and Ovarian Cancer Syndrome | 2 | D061325 | ClinicalTrials |
Sarcoma | 2 | D012509 | ClinicalTrials |
Hemangiosarcoma | 2 | D006394 | ClinicalTrials |
Hemangioendothelioma, Epithelioid | 2 | D018323 | ClinicalTrials |
Solitary Fibrous Tumors | 2 | D054364 | ClinicalTrials |
Melanoma | 1 | D008545 | ClinicalTrials |
Carcinoma, Renal Cell | 1 | D002292 | ClinicalTrials |
Ovarian Neoplasms | 1 | D010051 | ClinicalTrials |
Melanoma | 1 | D008545 | ClinicalTrials |
Fallopian Tube Neoplasms | 1 | D005185 | ClinicalTrials |
Resources | Reference |
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CAS NUMBER | 253128-41-5 |
ChEBI | 63587 |
ChEMBL | CHEMBL1683590 |
DrugBank | DB08871 |
DrugCentral | 4171 |
FDA SRS | LR24G6354G |
Guide to Pharmacology | 6813 |
PDB | 6K9 |
PubChem | 11354606 |
SureChEMBL | SCHEMBL15783821 |
ZINC | ZINC000169344691 |