Synonyms: | |
Status: | Approved (1991) |
Entry Type: | Small molecule |
Molecule Category: | Parent Prodrug |
ATC: | C09AA09 |
UNII: | R43D2573WO |
InChI Key | BIDNLKIUORFRQP-XYGFDPSESA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C30H46NO7P |
Molecular Weight | 563.67 |
AlogP | 6.12 |
Hydrogen Bond Acceptor | 6.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 14.0 |
Polar Surface Area | 110.21 |
Molecular species | ACID |
Aromatic Rings | 1.0 |
Heavy Atoms | 39.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
Protease
Metallo protease
Metallo protease MAE clan
Metallo protease M2 family
|
- | 1 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Diabetic Nephropathies | 2 | D003928 | ClinicalTrials |
Hypertension | 2 | D006973 | ClinicalTrials |
Heart Diseases | 2 | D006331 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 98048-97-6 |
ChEMBL | CHEMBL3039598 |
DrugCentral | 1245 |
FDA SRS | R43D2573WO |
Guide to Pharmacology | 6456 |
PubChem | 45357796 |
SureChEMBL | SCHEMBL5928355 |
ZINC | ZINC000003977764 |