| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 5829E3D9I9 |
Structure
| InChI Key | GJXWDTUCERCKIX-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C4H10NO5P |
| Molecular Weight | 183.1 |
| AlogP | -0.6 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 98.07 |
| Molecular species | ACID |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 11.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | 20-48 | 40 | 140 | - | |
|
Enzyme
|
- | 20-48 | 40 | 140 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Malaria | 3 | D008288 | ClinicalTrials |
| Malaria, Falciparum | 2 | D016778 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 443725 |
| ChEMBL | CHEMBL203125 |
| DrugBank | DB02948 |
| EPA CompTox | DTXSID70216712 |
| FDA SRS | 5829E3D9I9 |
| Guide to Pharmacology | 9739 |
| PDB | FOM |
| PubChem | 572 |
| SureChEMBL | SCHEMBL301404 |
| ZINC | ZINC000012502867 |
CONTENTS