| Status: | Approved (2008) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent Prodrug |
| UNII: | LZ257RZP7K |
Structure
| InChI Key | QVNNONOFASOXQV-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C13H21O5P |
| Molecular Weight | 288.28 |
| AlogP | 3.38 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 75.99 |
| Molecular species | ACID |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 19.0 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Genital Neoplasms, Male | 3 | D005834 | ClinicalTrials |
| Status Epilepticus | 3 | D013226 | ClinicalTrials |
| Delirium | 3 | D003693 | ClinicalTrials |
| Severe Acute Respiratory Syndrome | 3 | D045169 | ClinicalTrials |
| Respiratory Distress Syndrome | 3 | D012128 | ClinicalTrials |
| Pruritus | 3 | D011537 | ClinicalTrials |
| Stroke | 3 | D020521 | ClinicalTrials |
| Subarachnoid Hemorrhage | 3 | D013345 | ClinicalTrials |
| Obesity | 3 | D009765 | ClinicalTrials |
| Brain Injuries | 3 | D001930 | ClinicalTrials |
| Liver Cirrhosis | 3 | D008103 | ClinicalTrials |
| Reperfusion Injury | 3 | D015427 | ClinicalTrials |
| Heart Diseases | 3 | D006331 | ClinicalTrials |
| Pain | 3 | D010146 | ClinicalTrials |
| Back Pain | 3 | D001416 | ClinicalTrials |
| Respiratory Insufficiency | 3 | D012131 | ClinicalTrials |
| Atrial Fibrillation | 3 | D001281 | ClinicalTrials |
| Hypertension | 3 | D006973 | ClinicalTrials |
| Coronary Disease | 2 | D003327 | ClinicalTrials |
| Wounds and Injuries | 2 | D014947 | ClinicalTrials |
| Leukemia | 2 | D007938 | ClinicalTrials |
| Postoperative Nausea and Vomiting | 2 | D020250 | ClinicalTrials |
| Hypotension | 2 | D007022 | ClinicalTrials |
| Depressive Disorder, Treatment-Resistant | 2 | D061218 | ClinicalTrials |
| Pulmonary Disease, Chronic Obstructive | 2 | D029424 | ClinicalTrials |
| Tonsillitis | 2 | D014069 | ClinicalTrials |
| Neoplasms | 2 | D009369 | ClinicalTrials |
| Migraine Disorders | 2 | D008881 | ClinicalTrials |
| Neural Tube Defects | 1 | D009436 | ClinicalTrials |
| Premature Birth | 1 | D047928 | ClinicalTrials |
| Renal Insufficiency, Chronic | 1 | D051436 | ClinicalTrials |
| Colorectal Neoplasms | 1 | D015179 | ClinicalTrials |
| Depressive Disorder | 1 | D003866 | ClinicalTrials |
| Obesity, Morbid | 1 | D009767 | ClinicalTrials |
| Amnesia | 1 | D000647 | ClinicalTrials |
| Inflammation | 1 | D007249 | ClinicalTrials |
| Renal Insufficiency | 1 | D051437 | ClinicalTrials |
| Psychomotor Agitation | 1 | D011595 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 258516-89-1 |
| ChEBI | 135193 |
| ChEMBL | CHEMBL1201766 |
| DrugBank | DB06716 |
| DrugCentral | 3249 |
| FDA SRS | LZ257RZP7K |
| Human Metabolome Database | HMDB0015661 |
| Guide to Pharmacology | 7475 |
| PubChem | 3038498 |
| SureChEMBL | SCHEMBL3821874 |
| ZINC | ZINC000002519740 |
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