FRUCTOSE

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: V06DC02
UNII: B986VTP17J

Structure
InChI Key RFSUNEUAIZKAJO-ARQDHWQXSA-N
Smile OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H12O6
Molecular Weight 180.16
AlogP -3.22
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 2.0
Polar Surface Area 110.38
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 12.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily
- - - - 46-66
Ion channel Ligand-gated ion channel Glycine receptor
12589 - - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Melanoma 2 D008545 ClinicalTrials
Obesity 2 D009765 ClinicalTrials
Non-alcoholic Fatty Liver Disease 2 D065626 ClinicalTrials
Hypoglycemia 1 D007003 ClinicalTrials

Related Entries

MCS

Cross References

Resources Reference
ChEBI 28645
ChEMBL CHEMBL604608
EPA CompTox DTXSID5023081
FDA SRS B986VTP17J
KEGG C02336
PDB FRU
PubChem 5984
SureChEMBL SCHEMBL3966
ZINC ZINC000001529270
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