| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 4HTE364XIK |
Structure
| InChI Key | MBWRLLRCTIYXDW-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C29H34Cl2N8O4 |
| Molecular Weight | 629.55 |
| AlogP | 5.48 |
| Hydrogen Bond Acceptor | 9.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 10.0 |
| Polar Surface Area | 124.19 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 43.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Kinase
Protein Kinase
TK protein kinase group
Tyrosine protein kinase FGFR family
|
- | 1060 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Carcinoma, Hepatocellular | 1 | D006528 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 1702259-66-2 |
| ChEMBL | CHEMBL3939295 |
| DrugBank | DB15169 |
| FDA SRS | 4HTE364XIK |
| PubChem | 118029202 |
| SureChEMBL | SCHEMBL16659467 |
| ZINC | ZINC000521836463 |
CONTENTS