| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | J01EA03 |
| UNII: | 42445HUU0O |
Structure
| InChI Key | HWJPWWYTGBZDEG-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C19H22N4O3 |
| Molecular Weight | 354.41 |
| AlogP | 2.43 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 105.51 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 26.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | 2-27 | - | 0-1 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Infections | 3 | D007239 | ClinicalTrials |
| Skin Diseases | 3 | D012871 | ClinicalTrials |
| Pneumonia, Ventilator-Associated | 2 | D053717 | ClinicalTrials |
Related Entries
MCS
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 192314-93-5 |
| ChEBI | 131751 |
| ChEMBL | CHEMBL134561 |
| DrugBank | DB06358 |
| DrugCentral | 4573 |
| FDA SRS | 42445HUU0O |
| Guide to Pharmacology | 10820 |
| PubChem | 213043 |
| SureChEMBL | SCHEMBL379386 |
CONTENTS