| Synonyms: | |
| Status: | Approved (1986) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| UNII: | GR88G0I6UL |
Structure
| InChI Key | OEXHQOGQTVQTAT-BHIXFJMTSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C20H30NO3+ |
| Molecular Weight | 332.46 |
| AlogP | 2.85 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 46.53 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 24.0 |
Pharmacology
| Primary Target | |
|---|---|
| M3 receptor |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Acetylcholine receptor
|
- | - | - | 0.7943 | - | |
|
Transcription factor
|
- | - | - | - | 35.2 | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC22 family of organic cation and anion transporters
|
- | - | - | - | 47.8-79.1 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Pulmonary Disease, Chronic Obstructive | 3 | D029424 | ClinicalTrials |
| Status Asthmaticus | 1 | D013224 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 60205-81-4 |
| ChEMBL | CHEMBL1621597 |
| DrugBank | DB00332 |
| DrugCentral | 1475 |
| EPA CompTox | DTXSID9048437 |
| FDA SRS | GR88G0I6UL |
| Guide to Pharmacology | 325 |
| KEGG | C07052 |
| SureChEMBL | SCHEMBL7862886 |
CONTENTS