Synonyms: | |
Status: | Approved (2007) |
Entry Type: | Protein |
Molecule Category: | Parent |
ATC: | H01CB03 |
UNII: | 0G3DE8943Y |
InChI Key | PUDHBTGHUJUUFI-SCTWWAJVSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C54H69N11O10S2 |
Molecular Weight | 1096.35 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Primary Target | |
---|---|
SST2 receptor | |
SST5 receptor |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Somatostatin receptor
|
- | - | - | 1 | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Neoplasms | 3 | D009369 | ClinicalTrials |
Acromegaly | 3 | D000172 | ClinicalTrials |
Malignant Carcinoid Syndrome | 3 | D008303 | ClinicalTrials |
Carcinoid Tumor | 3 | D002276 | ClinicalTrials |
Endocrine Gland Neoplasms | 3 | D004701 | ClinicalTrials |
Polycystic Kidney, Autosomal Dominant | 3 | D016891 | ClinicalTrials |
Carcinoid Heart Disease | 3 | D002275 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 3 | D064129 | ClinicalTrials |
Carcinoid Tumor | 3 | D002276 | ClinicalTrials |
Rectal Neoplasms | 3 | D012004 | ClinicalTrials |
Pituitary Neoplasms | 3 | D010911 | ClinicalTrials |
Graves Ophthalmopathy | 2 | D049970 | ClinicalTrials |
Hyperglycemia | 2 | D006943 | ClinicalTrials |
Esophagitis, Peptic | 2 | D004942 | ClinicalTrials |
Intestinal Diseases | 2 | D007410 | ClinicalTrials |
Diarrhea | 2 | D003967 | ClinicalTrials |
Carcinoma, Merkel Cell | 2 | D015266 | ClinicalTrials |
Carcinoma, Hepatocellular | 2 | D006528 | ClinicalTrials |
Intestinal Obstruction | 2 | D007415 | ClinicalTrials |
Dumping Syndrome | 2 | D004377 | ClinicalTrials |
Neuroendocrine Tumors | 0 | D018358 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 108736-35-2 |
ChEMBL | CHEMBL1201185 |
EPA CompTox | DTXSID60897514 |
FDA SRS | 0G3DE8943Y |
Guide to Pharmacology | 2031 |
PubChem | 6918011 |