LUMICITABINE

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: BNW5PQ52G1

Structure
InChI Key MJVKYGMNSQJLIN-KYZVSKTDSA-N
Smile CC(C)C(=O)OC[C@@]1(CCl)O[C@@H](n2ccc(N)nc2=O)[C@H](F)[C@@H]1OC(=O)C(C)C
InChI
InChI=1S/C18H25ClFN3O6/c1-9(2)15(24)27-8-18(7-19)13(28-16(25)10(3)4)12(20)14(29-18)23-6-5-11(21)22-17(23)26/h5-6,9-10,12-14H,7-8H2,1-4H3,(H2,21,22,26)/t12-,13+,14-,18-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H25ClFN3O6
Molecular Weight 433.86
AlogP 1.44
Hydrogen Bond Acceptor 9.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 7.0
Polar Surface Area 122.74
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 29.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR RNA-directed RNA polymerase L inhibitor PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Respiratory Syncytial Virus Infections 2 D018357 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 1445385-02-3
ChEMBL CHEMBL3417258
DrugBank DB14808
FDA SRS BNW5PQ52G1
PubChem 89658382
SureChEMBL SCHEMBL15070623
ZINC ZINC000147003908
CONTENTS