MAVACAMTEN

Search structure
Synonyms:
Status: Approved (2022)
Entry Type: Small molecule
Molecule Category: Parent
UNII: QX45B99R3J

Structure
InChI Key RLCLASQCAPXVLM-NSHDSACASA-N
Smile CC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O
InChI
InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H19N3O2
Molecular Weight 273.34
AlogP 2.29
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 66.89
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 20.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Cardiomyopathy, Hypertrophic 3 D002312 ClinicalTrials
Heart Failure 2 D006333 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 1642288-47-8
ChEMBL CHEMBL4297517
DrugBank DB14921
FDA SRS QX45B99R3J
Guide to Pharmacology 11265
PubChem 117761397
SureChEMBL SCHEMBL16320785
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