NANDROLONE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: Parent
ATC: A14AB01
UNII: 6PG9VR430D

Structure
InChI Key NPAGDVCDWIYMMC-IZPLOLCNSA-N
Smile C[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2O
InChI
InChI=1S/C18H26O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-17,20H,2-9H2,1H3/t13-,14+,15+,16-,17-,18-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H26O2
Molecular Weight 274.4
AlogP 3.49
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 0.0
Polar Surface Area 37.3
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 20.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - -
Enzyme Kinase Protein Kinase Atypical protein kinase group Atypical protein kinase PDHK subfamily
- 120000 - - -
Enzyme Transferase
- - - - 13.77
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - -17.61-3.26
Secreted protein
- - 501.19 724.44 -
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 3
- 171.5 - 22.4 -
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 4
- 3.149 - 2.099 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC22 family of organic cation and anion transporters
- 35100 - - 79.3

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Anemia, Aplastic 3 D000741 ClinicalTrials

Related Entries

MCS

Scaffolds

Salt

Cross References

Resources Reference
CAS NUMBER 434-22-0
ChEBI 7466
ChEMBL CHEMBL757
DrugBank DB13169
DrugCentral 1879
EPA CompTox DTXSID7023350
FDA SRS 6PG9VR430D
Human Metabolome Database HMDB02725
Guide to Pharmacology 6949
KEGG C07254
PDB 6VW
PharmGKB PA164746281
PubChem 9904
SureChEMBL SCHEMBL20140
ZINC ZINC000003814379
CONTENTS