| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| ATC: | M01AE18 |
| UNII: | V24GR4LI3I |
Structure
| InChI Key | AKFJWRDCWYYTIG-ZDUSSCGKSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C18H21NO6 |
| Molecular Weight | 347.37 |
| AlogP | 3.48 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 87.9 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 25.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Cyclooxygenase inhibitor | PubMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Osteoarthritis | 3 | D010003 | ClinicalTrials |
| Osteoarthritis, Hip | 3 | D015207 | ClinicalTrials |
| Liver Diseases | 1 | D008107 | ClinicalTrials |
| Renal Insufficiency | 1 | D051437 | ClinicalTrials |
Related Entries
MCS
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 163133-43-5 |
| ChEBI | 76254 |
| ChEMBL | CHEMBL2103831 |
| DrugBank | DB06682 |
| DrugCentral | 4674 |
| EPA CompTox | DTXSID20167523 |
| FDA SRS | V24GR4LI3I |
| Guide to Pharmacology | 9551 |
| PubChem | 9884642 |
| SureChEMBL | SCHEMBL1170879 |
| ZINC | ZINC000001541804 |
CONTENTS