NEMONOXACIN

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: J01MB08
UNII: P94L0PVO94

Structure
InChI Key AVPQPGFLVZTJOR-RYUDHWBXSA-N
Smile COc1c(N2C[C@@H](C)C[C@H](N)C2)ccc2c(=O)c(C(=O)O)cn(C3CC3)c12
InChI
InChI=1S/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H25N3O4
Molecular Weight 371.44
AlogP 2.22
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 97.79
Molecular species ZWITTERION
Aromatic Rings 2.0
Heavy Atoms 27.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial DNA gyrase inhibitor PubMed Other PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Pneumonia 3 D011014 ClinicalTrials
Pneumonia, Bacterial 3 D018410 ClinicalTrials
Infections 2 D007239 ClinicalTrials
Kidney Diseases 1 D007674 ClinicalTrials
Liver Diseases 1 D008107 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 378746-64-6
ChEBI 136053
ChEMBL CHEMBL1213456
DrugBank DB06600
DrugCentral 5079
FDA SRS P94L0PVO94
Guide to Pharmacology 10836
PubChem 11993740
SureChEMBL SCHEMBL1006373
ZINC ZINC000040435195
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