| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | TK694ZFS57 |
Structure
| InChI Key | SDOOGTHIDFZUNM-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C27H40ClN3O |
| Molecular Weight | 458.09 |
| AlogP | 6.63 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 44.37 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 31.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
|
- | 52 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Cushing Syndrome | 2 | D003480 | ClinicalTrials |
| Adrenal Hyperplasia, Congenital | 2 | D000312 | ClinicalTrials |
| Adrenal Cortex Neoplasms | 1 | D000306 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL542103 |
| EPA CompTox | DTXSID10158389 |
| FDA SRS | TK694ZFS57 |
| PubChem | 131678 |
| SureChEMBL | SCHEMBL5973583 |
CONTENTS