| Status: | Approved (1981) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | C02DD01 |
| UNII: | 169D1260KM |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C5FeN6O-2 |
| Molecular Weight | 215.94 |
| AlogP | None |
| Hydrogen Bond Acceptor | None |
| Hydrogen Bond Donor | None |
| Number of Rotational Bond | None |
| Polar Surface Area | None |
| Molecular species | None |
| Aromatic Rings | None |
| Heavy Atoms | None |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Epigenetic regulator
Eraser
Histone deacetylase
HDAC class IIb
|
- | - | - | - | -12.54-10.65 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Myocardial Infarction | 2 | D009203 | ClinicalTrials |
| Hypotension | 2 | D007022 | ClinicalTrials |
| Depressive Disorder | 2 | D003866 | ClinicalTrials |
| Hypotension, Orthostatic | 1 | D007024 | ClinicalTrials |
| Orthostatic Intolerance | 1 | D054971 | ClinicalTrials |
Related Entries
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 15078-28-1 |
| ChEBI | 7596 |
| ChEMBL | CHEMBL2097081 |
| DrugBank | DB00325 |
| FDA SRS | 169D1260KM |
| Human Metabolome Database | HMDB14470 |
| PubChem | 11963622 |
CONTENTS