Synonyms: | |
Status: | Approved (1988) |
Entry Type: | Protein |
Molecule Category: | Parent |
ATC: | H01CB02 |
UNII: | RWM8CCW8GP |
InChI Key | DEQANNDTNATYII-OULOTJBUSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C49H66N10O10S2 |
Molecular Weight | 1019.26 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Somatostatin receptor
|
- | 22 | - | 0 | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Pancreatic Neoplasms | 3 | D010190 | ClinicalTrials |
Malignant Carcinoid Syndrome | 3 | D008303 | ClinicalTrials |
Carcinoid Tumor | 3 | D002276 | ClinicalTrials |
Polycystic Kidney, Autosomal Dominant | 3 | D016891 | ClinicalTrials |
Neuroendocrine Tumors | 3 | D018358 | ClinicalTrials |
Diarrhea | 3 | D003967 | ClinicalTrials |
Carcinoma, Hepatocellular | 3 | D006528 | ClinicalTrials |
Neuroendocrine Tumors | 3 | D018358 | ClinicalTrials |
Acromegaly | 3 | D000172 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
Thymoma | 2 | D013945 | ClinicalTrials |
Neoplasms | 2 | D009369 | ClinicalTrials |
Neoplasms | 2 | D009369 | ClinicalTrials |
Adenoma, Islet Cell | 2 | D007516 | ClinicalTrials |
Meningioma | 2 | D008579 | ClinicalTrials |
Telangiectasia, Hereditary Hemorrhagic | 2 | D013683 | ClinicalTrials |
Carcinoma, Neuroendocrine | 2 | D018278 | ClinicalTrials |
Intestinal Obstruction | 2 | D007415 | ClinicalTrials |
Idiopathic Pulmonary Fibrosis | 1 | D054990 | ClinicalTrials |
Infections | 1 | D007239 | ClinicalTrials |
Migraine Disorders | 1 | D008881 | ClinicalTrials |
Hypotension, Orthostatic | 1 | D007024 | ClinicalTrials |
Irritable Bowel Syndrome | 1 | D043183 | ClinicalTrials |
Obesity | 1 | D009765 | ClinicalTrials |
Gastrointestinal Hemorrhage | 1 | D006471 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 83150-76-9 |
ChEMBL | CHEMBL1680 |
DrugBank | DB00104 |
FDA SRS | RWM8CCW8GP |
Guide to Pharmacology | 2055 |
PubChem | 448601 |
SureChEMBL | SCHEMBL10044649 |