PF-04937319

Search structure
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 7E99B9ZM19

Structure
InChI Key MASKQITXHVYVFL-UHFFFAOYSA-N
Smile Cc1cnc(NC(=O)c2cc(Oc3cnc(C(=O)N(C)C)nc3)c3cc(C)oc3c2)cn1
InChI
InChI=1S/C22H20N6O4/c1-12-8-24-19(11-23-12)27-21(29)14-6-17-16(5-13(2)31-17)18(7-14)32-15-9-25-20(26-10-15)22(30)28(3)4/h5-11H,1-4H3,(H,24,27,29)

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H20N6O4
Molecular Weight 432.44
AlogP 3.38
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 123.34
Molecular species NEUTRAL
Aromatic Rings 4.0
Heavy Atoms 32.0

Indications

Mesh Heading Maximum Phase Reference
Diabetes Mellitus; Diabetes Mellitus, Type 2 Phase 1 ClinicalTrials
Diabetes Mellitus; Diabetes Mellitus, Type 2 Phase 1 ClinicalTrials

Cross References

Resources Reference
CAS NUMBER 1245603-92-2
ChEMBL CHEMBL2165615
DrugBank DB15009
FDA SRS 7E99B9ZM19
PDB S41
PubChem 46916694
SureChEMBL SCHEMBL1720691
ZINC ZINC000068246554
CONTENTS