PF-05241328

Search structure
Synonyms:
Status: Phase 1
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 8RAL5N48VT

Structure
InChI Key RVTSXVZXEGFIPW-UHFFFAOYSA-N
Smile Cc1nn(-c2cnc(OCC(C)C)c(Cl)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12
InChI
InChI=1S/C19H21ClN4O4S/c1-11(2)10-28-19-16(20)8-14(9-21-19)24-17-6-5-13(7-15(17)12(3)22-24)18(25)23-29(4,26)27/h5-9,11H,10H2,1-4H3,(H,23,25)

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H21ClN4O4S
Molecular Weight 436.92
AlogP 3.11
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 6.0
Polar Surface Area 103.18
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 29.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Voltage-gated sodium channel
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Cross References

Resources Reference
CAS NUMBER 1387633-03-5
ChEMBL CHEMBL4279521
DrugBank DB15124
FDA SRS 8RAL5N48VT
PubChem 68109743
SureChEMBL SCHEMBL10324699
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