Synonyms: | |
Status: | Approved (2017) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
UNII: | 2WU922TK3L |
InChI Key | VJYSBPDEJWLKKJ-NLIMODCCSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C57H65F5N10O8 |
Molecular Weight | 1113.2 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Nonstructural protein 5A inhibitor | FDA |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
|
0-0 | - | - | - | - | |
Unclassified protein
|
0-0 | - | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Hepatitis C, Chronic | 4 | D019698 | ClinicalTrials |
Hepatitis C | 3 | D006526 | ClinicalTrials |
Liver Diseases | 1 | D008107 | ClinicalTrials |
Kidney Diseases | 1 | D007674 | ClinicalTrials |
Renal Insufficiency, Chronic | 0 | D051436 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 1353900-92-1 |
ChEMBL | CHEMBL3545123 |
DrugBank | DB13878 |
DrugCentral | 5244 |
FDA SRS | 2WU922TK3L |
Guide to Pharmacology | 11268 |
PubChem | 58031952 |
SureChEMBL | SCHEMBL2756579 |