| Synonyms: | |
| Status: | Phase 2 |
| Entry Type: | Antibody |
| Molecule Category: | UNKNOWN |
| UNII: | AF75XOF6W3 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Lymphocyte activation gene 3 protein inhibitor |
| Primary Target | |
|---|---|
| LAG3 (CD223) |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Colorectal Neoplasms | 3 | D015179 | ClinicalTrials |
| Colorectal Neoplasms | 3 | D015179 | ClinicalTrials |
| Melanoma | 3 | D008545 | ClinicalTrials |
| Melanoma | 3 | D008545 | ClinicalTrials |
| Melanoma | 3 | D008545 | ClinicalTrials |
| Colorectal Neoplasms | 3 | D015179 | ClinicalTrials |
| Carcinoma, Renal Cell | 2 | D002292 | ClinicalTrials |
| Nasopharyngeal Carcinoma | 2 | D000077274 | ClinicalTrials |
| Multiple Myeloma | 2 | D009101 | ClinicalTrials |
| Carcinoma, Squamous Cell | 2 | D002294 | ClinicalTrials |
| Carcinoma, Hepatocellular | 2 | D006528 | ClinicalTrials |
| Leukemia, Myeloid, Acute | 2 | D015470 | ClinicalTrials |
| Neoplasms | 2 | D009369 | ClinicalTrials |
| Chordoma | 2 | D002817 | ClinicalTrials |
| Carcinoma, Squamous Cell | 2 | D002294 | ClinicalTrials |
| Colonic Neoplasms | 2 | D003110 | ClinicalTrials |
| Neoplasms | 2 | D009369 | ClinicalTrials |
| Uveal Melanoma | 2 | D000098943 | ClinicalTrials |
| Carcinoma, Merkel Cell | 2 | D015266 | ClinicalTrials |
| Liver Neoplasms | 2 | D008113 | ClinicalTrials |
| Carcinoma, Non-Small-Cell Lung | 2 | D002289 | ClinicalTrials |
| Carcinoma, Basal Cell | 2 | D002280 | ClinicalTrials |
| Sarcoma | 2 | D012509 | ClinicalTrials |
| Stomach Neoplasms | 2 | D013274 | ClinicalTrials |
| Lymphoma | 1 | D008223 | ClinicalTrials |
| Lymphoma, Large B-Cell, Diffuse | 1 | D016403 | ClinicalTrials |
| Esophageal Neoplasms | 1 | D004938 | ClinicalTrials |
| Hematologic Neoplasms | 1 | D019337 | ClinicalTrials |
| Glioblastoma | 1 | D005909 | ClinicalTrials |
| Lymphoma, Follicular | 1 | D008224 | ClinicalTrials |
| Gliosarcoma | 1 | D018316 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 1673516-98-7 |
| ChEMBL | CHEMBL3990044 |
| FDA SRS | AF75XOF6W3 |
| Guide to Pharmacology | 9536 |
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