| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 467LU0UCUW |
Structure
| InChI Key | HKFMQJUJWSFOLY-OAQYLSRUSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C22H21FN2O |
| Molecular Weight | 348.42 |
| AlogP | 4.37 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 34.15 |
| Molecular species | BASE |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 26.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Dopamine receptor
|
- | - | - | 19 | - | |
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Serotonin receptor
|
78 | - | - | 2138 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Movement Disorders | 3 | D009069 | ClinicalTrials |
| Rett Syndrome | 2 | D015518 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 351862-32-3 |
| ChEMBL | CHEMBL220808 |
| DrugBank | DB06454 |
| FDA SRS | 467LU0UCUW |
| PubChem | 6918388 |
| SureChEMBL | SCHEMBL120080 |
| ZINC | ZINC000000021067 |
CONTENTS