| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 24DSZ1VN92 |
Structure
| InChI Key | PGXYIBJJCLWJST-MUUNZHRXSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C31H33ClN2O3 |
| Molecular Weight | 517.07 |
| AlogP | 6.53 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 76.54 |
| Molecular species | BASE |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 37.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Voltage-gated ion channel
Potassium channels
Voltage-gated potassium channel
|
- | 1600 | - | - | - | |
|
Other cytosolic protein
|
- | 0-607 | 543-30035 | 1 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Hodgkin Disease | 1 | D006689 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
| Lymphoma, Non-Hodgkin | 1 | D008228 | ClinicalTrials |
Related Entries
MCS
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL2325429 |
| FDA SRS | 24DSZ1VN92 |
| PDB | 6LX |
| PubChem | 9936388 |
| SureChEMBL | SCHEMBL645543 |
| ZINC | ZINC000034039290 |
CONTENTS