SLX-4090

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: F84YQX13FV

Structure
InChI Key AZUIUVJESCFSLJ-UHFFFAOYSA-N
Smile COc1cccc(C(=O)Nc2ccc3c(c2)CCN(C(=O)Oc2ccccc2)C3)c1-c1ccc(C(F)(F)F)cc1
InChI
InChI=1S/C31H25F3N2O4/c1-39-27-9-5-8-26(28(27)20-10-13-23(14-11-20)31(32,33)34)29(37)35-24-15-12-22-19-36(17-16-21(22)18-24)30(38)40-25-6-3-2-4-7-25/h2-15,18H,16-17,19H2,1H3,(H,35,37)

Physicochemical Descriptors

Property Name Value
Molecular Formula C31H25F3N2O4
Molecular Weight 546.55
AlogP 7.19
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 67.87
Molecular species NEUTRAL
Aromatic Rings 4.0
Heavy Atoms 40.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Microsomal triglyceride transfer protein inhibitor Other PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 2 D003924 ClinicalTrials
Hyperlipidemias 2 D006949 ClinicalTrials
Hypertriglyceridemia 2 D015228 ClinicalTrials
Hyperlipoproteinemia Type I 2 D008072 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
CAS NUMBER 913541-47-6
ChEMBL CHEMBL4297326
DrugBank DB05678
FDA SRS F84YQX13FV
PubChem 53497429
SureChEMBL SCHEMBL14585862
ZINC ZINC000072316409
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