Synonyms: | |
Status: | Approved (2004) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
ATC: | G04BD08 |
UNII: | A8910SQJ1U |
InChI Key | FBOUYBDGKBSUES-VXKWHMMOSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C23H26N2O2 |
Molecular Weight | 362.47 |
AlogP | 3.86 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 2.0 |
Polar Surface Area | 32.78 |
Molecular species | BASE |
Aromatic Rings | 2.0 |
Heavy Atoms | 27.0 |
Primary Target | |
---|---|
M2 receptor | |
M3 receptor |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Auxiliary transport protein
Slow voltage-gated potassium channel accessory protein family
|
- | 31623 | - | - | - | |
Ion channel
Voltage-gated ion channel
Potassium channels
Voltage-gated potassium channel
|
- | 251-1585 | - | - | - | |
Ion channel
Voltage-gated ion channel
Voltage-gated calcium channel
|
- | 4300 | - | - | - | |
Ion channel
Voltage-gated ion channel
Voltage-gated sodium channel
|
- | 6310 | - | - | - | |
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Acetylcholine receptor
|
- | - | - | 10 | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Urinary Incontinence | 4 | D014549 | ClinicalTrials |
Urinary Bladder, Overactive | 3 | D053201 | ClinicalTrials |
Prostatic Hyperplasia | 3 | D011470 | ClinicalTrials |
Urinary Incontinence, Urge | 1 | D053202 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 242478-37-1 |
ChEBI | 135530 |
ChEMBL | CHEMBL1734 |
DrugBank | DB01591 |
DrugCentral | 2457 |
EPA CompTox | DTXSID3048289 |
FDA SRS | A8910SQJ1U |
Guide to Pharmacology | 7483 |
PubChem | 154059 |
SureChEMBL | SCHEMBL188493 |
ZINC | ZINC000003936683 |