| Synonyms: | |
| Status: | Phase 3 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | G4186B906P |
Structure
| InChI Key | LXANPKRCLVQAOG-NSHDSACASA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C11H9FN2O3 |
| Molecular Weight | 236.2 |
| AlogP | 0.64 |
| Hydrogen Bond Acceptor | 3.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 0.0 |
| Polar Surface Area | 67.43 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 17.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | 17-8000 | - | - | 36-95 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Diabetic Retinopathy | 3 | D003930 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 68367-52-2 |
| ChEBI | 102029 |
| ChEMBL | CHEMBL266497 |
| DrugBank | DB02712 |
| EPA CompTox | DTXSID0023587 |
| FDA SRS | G4186B906P |
| Guide to Pharmacology | 7415 |
| PDB | SBI |
| PubChem | 337359 |
| SureChEMBL | SCHEMBL48877 |
| ZINC | ZINC000000002070 |
CONTENTS